中国听力语言康复科学杂志Issue(3)：174-177,4.DOI:10.3969/j.issn.1672-4933.2014.03.005
高压氧综合治疗突发性耳聋预后相关因素分析
Factors Relevant to the Prognosis of Patients with Sudden Deafness after Hyperbaric Oxygen Therapy
李琴 1吴嗣洪 2唐守英 1张惠华 1曹晓燕 1葛秀英1
作者信息
- 1. 上海市奉贤区中心医院 上海 201499
- 2. 上海交通大学附属新华医院 上海 200092
- 折叠
摘要
Abstract
Objective To establish a scoring model that predicts the prognosis of patients with sudden deafness after hyperbaric oxygen therapy based on clinical data and to evaluate the efficacy of the model. Methods 188 patients with sudden deafness(221 ears)who received hyperbaric oxygen therapy were divided into two groups: 168 patients(201 ears) in training group and 20 patients(20 ears)in testing group. With a self-controlled experimental design, the training group were divided into the effective group and ineffective group. Chi-square test was applied to choose statistically significant risk factors which were used to establish a scoring model. Receiver operator characteristic (ROC) curve was then used to analyze the scoring model. Results The factors that had adverse effects on the prognosis of patients with sudden deafness after hyperbaric oxygen therapy included sudden deafness with vertigo, descending/completely deaf audiogram, prehospital delay time≥15 d, hyperbaric oxygen therapy<2 courses, beginning time of treatment≥fifteen days after onset, average hearing loss at the first visit≥60 dB HL, sudden deafness with HBP(high blood pressure)/DM(diabetes mellitus)or both. The ROC curve analysis revealed that the area under the curve (AUC) for the scoring model was 0.967, which was significantly different from the AUC(0.5) under the completely random circumstances(P<0.05). The appraisal of prospective misjudge possibility was applied to the scoring model in testing samples and the results showed the misjudgement rate was about 10%. Conclusion This scoring model based on clinical data can be used to predict the prognosis of patients with sudden deafness after hyperbaric oxygen therapy.关键词
突发性耳聋/高压氧治疗/预后/相关因素Key words
Sudden deafness/Hyperbaric oxygen therapy/Prognosis/Relevant factor引用本文复制引用
李琴,吴嗣洪,唐守英,张惠华,曹晓燕,葛秀英..高压氧综合治疗突发性耳聋预后相关因素分析[J].中国听力语言康复科学杂志,2014,(3):174-177,4.
