中国斜视与小儿眼科杂志Issue(3)：26-31,6.
弱视治疗前后对比敏感度的分析
Analysis of Contrast sensitivity in amblyopia before treatment
贾趁霞 1胡俊喜 2闫义涛 2周予兰 2王晓丽 2刘向玲 3王瑞虎2
作者信息
- 1. 453001 河南长垣县人民医院眼科
- 2. 新乡医学院第一附属医院眼科
- 3. 新乡医学院第三附属医院眼科
- 折叠
摘要
Abstract
Objective Investigate contrast sensitivity (CS) on the eyes of amblyopic and treated amblyopic patients. Methods Contrast sensitivity at spatial frequencies (1.5, 3,6,12,18 cycles/degree) was measured in 47 ambly-opic children (79 eyes) and 40 normal children (80 eyes,visual acuity ≥1.0) which act as the control group on the Optec 6500 Functional Visual Analyzer (Stereo Optec Co. Inc,America) .For the amblyopic children,measurements were done before and after 5 months treatment.All subjects were tested with a natural pupil under normal lighting. The contrast sensitivity was tested monocularly on both eyes of amblyopic patients. The eyes with better visual acuity were firstly checked, and subsequent the worse ones. The saved measurement results were handled through the corre-sponding data processing software to obtain the CS curves. The changes in CS values in normal control eyes and am-blyopic eyes before and after treatment at different fre-quencies were analyzed by SPSS17.0 statistical software. Result ( 1) The peaks of contrast sensitivity function (CSF) curves for normal children were located at the spa-tial frequency of 6 c/d. The CSF decreased at the lower or higher spatial frequencies,therefore the CSF curve diagram showed an inverted“U”shape. The cut-off frequency was 25 c/d by extrapolating from the curve at high spatial fre-quency. (2) In mild amblyopia patients: The amplitude and CS obviously decreased at high spatial frequencies com-pared with the normal control group. The difference between the two groups is statistically significant (P<0.05) .Post treatment the CS obviously increased compared with that before treatment,and the difference is significant (amblyopi-a;treatment;contrast sensitivity<0.05) .There were no statistically significant differences between the normal control group and those amblyopic groups. (3) In moderate amblyopia patients: The CS decreased at medium and high spatial frequencies, which were statistically different (P <0.05) from the normal group. After treatment the CS increased. There were no statistically significant differences between the normal control group and those amblyopic patients. (4) In severe amblyopia patients The CS was lower in low, medium and high spatial frequencies than the control group. There was significant difference in the medium and high spatial frequencies,not in the low frequencies. After the treatment,CS is improved with no statistically significant differences. Comparison between the normal group and am-blyopic group demonstrated no statistically significant differences. (5) The extent and efficacy of amblyopia: The more severe the amblyopia degree is, the worse the curative effect is. The basic cure rates in mild and medium amblyopia were 90% (18 eyes) and 86.5% (32 eyes),respectively. Basically there were no cured patients in the severe ambly-opic groups. There were obvious difference among the three groups (P <0.05) .Conclusion CS is a comprehensive and sensitive detection method for visual function and provides a reliable methords in diagnosing early amblyopia,monitor-ing curative effect and guiding treatment.关键词
弱视/治疗/对比敏感度Key words
amblyopia treatment/contrast/sensitivity引用本文复制引用
贾趁霞,胡俊喜,闫义涛,周予兰,王晓丽,刘向玲,王瑞虎..弱视治疗前后对比敏感度的分析[J].中国斜视与小儿眼科杂志,2014,(3):26-31,6.
