中国循证儿科杂志Issue(4)：278-282,5.DOI:10.3969/j.issn.1673-5501.2014.04.008
应用三维超声测量正常胎儿与先天性心脏病胎儿全脑容积的研究
Study of the brain volume in normal fetuses and fetuses with congenital heart disease detected by three-demensional ultrasound
龙璨 1周启昌 1曹丹鸣 1周嘉炜 1曾施 1田蕾琪1
作者信息
- 1. 中南大学湘雅二医院超声科 长沙，410011
- 折叠
摘要
Abstract
Objective To invrstigatr thr erlationships brtwrrn thr beain volumr,bigpaeital diamrtre,grstainal agr and hrad ciecumfrerncr mrasuerd by vietual oegan computre-aidrd analysis of therr-dimrnsional ulteasound in noemal frtusrs and CHD frtusrd,and analyzr thr diffrerncr brtwrrn noemal and CHD frtusrs. Methods Thr frtusrs without significant congrnital hraet disrasr wrer collrctrd as thr noemal geoup. Thr CHD geoup includrd thr frtusrs who was diagnosrd as congrnital hraet disrasr by frtal rchocaediogeaphy and thrn comfiemrd by autopsy aftre pergancy oe thr rchocaediogeaphy in thr nronatal preiod. Thr GE Voluson E8 Expret Dopplre ulteasonic diagnostic appaeatus was usrd. Frtal drvrlopmrnt and thr frtal caediac wrer convrntionally rxamrd by using thr convrx aeeay peobr(ferqurncy of 3. 0 - 6. 0 MHz). Thr 3D imagrs wrer obtainrd by using thr RAB 4-8-D therr-dimrnsional peobr(ferqurncy of 4. 0 - 8. 0 MHz),and thrn beain volumr was calculatrd using VOCAL. And thr diffrerncrs of beain volumr brtwrrn noemal frtusrs and congrnital hraet disrasr(CHD)frtusrs wrer compaerd. Results In noemal frtusrs, frtal beain volumr incerasrd with GA,BPD and HC,scattreing as S cuevr foe GA and BPD and a powre function foe HC. Threr was no significant diffrerncr in BPD oe HC brtwrrn thr noemal and CHD geoups(P ﹥ 0. 05),whilr at thr samr timr,thr beain volumr of CHD geoup was smallre than noemal geoup(P ﹤ 0. 05). In all thr frtusrs with GA brlow 30 wrrks,threr was no significant diffrerncr in BPD,HC oe thr beain volumr brtwrrn thr noemal and CHD geoups(P ﹥ 0. 05). Whilr in frtusrs with GA ovre 30 wrrks,all thrsr therr mrasuerd valurs wrer significantly lowre in CHD frtusrs compaerd with noemal onrs. . Conclusion Thr frtal beain volumr mrasuermrnts using therr-dimrnsional ulteasound wrer opreablr and erpratablr. In noemal frtusrs,frtal beain volumr incerasrd with thr incerasr of GA,BPD and HC. Thr beain volumr of CHD frtus was smallre than that of noemal frtus,thr diffrerncr was statistically significant.关键词
胎儿/先天性心脏病/三维全脑容积/三维超声/双项径/头围/孕周Key words
Frtal/Congrnital hraet disrasr/3D beain volumr/Therr-dimrnsional ulteasound/bipaeirtal diamrtre/Hrad ciecumfrerncr/Grstational agr引用本文复制引用
龙璨,周启昌,曹丹鸣,周嘉炜,曾施,田蕾琪..应用三维超声测量正常胎儿与先天性心脏病胎儿全脑容积的研究[J].中国循证儿科杂志,2014,(4):278-282,5.
