中国药房Issue(18)：2506-2508,2509,4.DOI:10.6039/j.issn.1001-0408.2015.18.21
基于马尔可夫模型比较丙戊酸钠、托吡酯和苯妥英钠治疗癫痫的经济性
Comparison of Economy among Antiepileptic Agents Sodium Valproate,Topiramate and Dipheninum Based on Markov Model
摘要
Abstract
OBJECTIVE:To compare economy among sodium valproate (VPA),topiramate (TPM) and dipheninum (DPH) in the treatment of epilepsy (EP). METHODS:Retrieved from ProQuest,PubMed,Springer,CJFD,VIP,Wanfang database,re-searches about economy among VPA,TPM and DPH in the treatment of EP were collected. TreeAge Pro 2011.1.0.12.1 software was used to establish Markov model,and cost-effectiveness ratios (CER) of them were calculated to evaluate their economy. RE-SULTS:CER of DPH,VPA,TPM were 29.99,2 664.52 and 6 657.25,in ascending order of DPH<VPA<TPM. CONCLU-SIONS:Only considering about the economics,DPH is the most economical and effective medicine in the treatment of epilepsy. Due to small number of studies,large-scale and high quality studies are required for further validation of the conclusion.关键词
经济性/马尔可夫模型/成本-效果分析Key words
Epilepsy/Markov model/Cost-effectiveness analysis分类
医药卫生引用本文复制引用
姜国云,高俊峰,李佳..基于马尔可夫模型比较丙戊酸钠、托吡酯和苯妥英钠治疗癫痫的经济性[J].中国药房,2015,(18):2506-2508,2509,4.基金项目
国家科技支撑计划课题 （）
