中国药房Issue(18)：2552-2553,2554,3.DOI:10.6039/j.issn.1001-0408.2015.18.36
GC-MS法测定爱维心口服液中麝香酮的含量
Content Determination of Muscone in the Aiweixin Oral Liquid by GC-MS
周泽 1李光 2李宜航 2何美捷1
作者信息
- 1. 重庆市大足区人民医院，重庆 402360
- 2. 中国医学科学院药用植物研究所云南分所，云南景洪 666100
- 折叠
摘要
Abstract
OBJECTIVE:To establish a method for the content determination of muscone in Aiweixin oral liquid. METHODS:After extracting sample by butanol,GC-MS was performed on the column of BD-17 MS with the volume temperature of 270 ℃;the carrier gas was helium with the sample size of 1 μl at the flow rate of 10 ml/min;the split ratio was 20∶1. EI was ion source with the electron energy of 70 eV,ion source temperature of 230 ℃ and quadrupole temperature of 150 ℃;the tuning mode was automatic tuning by quality full scanning with the threshold value of 30 in the range of 30-600 aum. RESULTS:The linear range of muscone was 12.216-61.08 ng(r=0.999 6);RSD of precision test was lower than 2% and the RSDs of reproducibility and stability tests were lower than 3%;the average recovery was 100.24%(RSD=1.58%,n=6). CONCLUSIONS:The method is sensitive, rapid and simple,and can be used for the content determination of muscone in Aiweixin oral lipid.关键词
麝香酮/爱维心口服液/气相色谱-质谱联用法Key words
Muscone/Aiweixin oral liquid/GC-MS分类
医药卫生引用本文复制引用
周泽,李光,李宜航,何美捷..GC-MS法测定爱维心口服液中麝香酮的含量[J].中国药房,2015,(18):2552-2553,2554,3.
