龚嘎蓝孜 1次仁旺姆 2索朗央宗 3白玛多吉 1多吉卓玛1
作者信息
- 1. 西藏大学医学院，拉萨 850000
- 2. 拉萨市疾病预防控制中心，拉萨 850000
- 3. 西藏自治区人民医院药剂科，拉萨 850000
- 折叠
摘要
Abstract
OBJECTIVE:To observe therapeutic efficacy and safety of Rhodiola rosea in the treatment of acute mountain sick-ness(AMS). METHODS:200 students with AMS in Tibet university from main land China,who had never been at high altitude before,were randomly divided into 3 groups by humber:R. rosea group(67 patients),Ginkgo biloba group(65 patients)and ac-etazolamide group(68 patients). Each group was given relevant medicine on the first day of inbound Tibet,morning and night,for consecutive 7 days. Clinical efficacy and ADR of 3 groups were observed and compared on first,third,fifth and seventh day. RE-SULTS:3 kinds of drugs were effective for AMS. On first,third,fifth and seventh day,AMS sore of R.rosea group was lower-than other 2 groups,there was statistically significant difference(P<0.05);On first and third day,AMS score of G.biloba group was lower than that of acetazolamide group,there was statistically significant difference(P<0.05),while there was no statistically significant difference between 2 groups on fifth and seveth day(P>0.05). On third,fifth and seventh day,the oxygen saturation (SaO2)of R. rosea group were higher than other 2 groups;while,heart rate(HR)was lower than other 2 groups,there was statis-tical significance (P<0.05);SaO2 and HR of G.biloba group and acetazolamide group had no statistically significant difference (P>0.05). No ADR was found in R. rosea group. CONCLUSIONS:R. rosea can reduce the severity of hypoxia,and it have good treatment effect on AMS,short cure time and good security.关键词
红景天/银杏叶/乙酰唑胺/急性高原反应/临床疗效Key words
Rhodiola rosea/Ginkgo biloba/Acetazolamide/Acute mountain sickness/Clinical efficacy分类
医药卫生
