中国药房Issue(20):2840-2842,3.DOI:10.6039/j.issn.1001-0408.2015.20.36
芒硝外敷联合顺铂腹腔灌注治疗老年结直肠癌恶性腹水的临床观察
Clinical Observation of Mirabilite Combined with Cisplatin Intraperitoneal in the Treatment of Elderly Colorectal Malignant Ascites
周元 1蒋红钢 1陆伯豪 1陈治横1
作者信息
- 1. 嘉兴市第一医院肿瘤外科,浙江嘉兴 314000
- 折叠
摘要
Abstract
OBJECTIVE:To observe the clinical efficacy and ADR of Mirabilite combined with intrapetitoneal in the treatment of elderly colorectal malignant ascites. METHODS:77 cases of patients with elderly colorectal malignant ascites were randomly di-vided into treatment group (n=40) and control group (n=37). The control group received the treatment of intraperitoneal alone, while the treatment group was based on the control group additionally received Mirabilite combined with intrapetitoneal. The clini-cal efficacy,quality of life (QOL),and ADR in 2 groups were compared and statistically analyzed. RESULTS:Compared with control group,the effective rate in treatment group was 77.5% and the disease control rate was 87.5%,with significant difference (P<0.05);the QOL score in treatment group was better than control group,with significant difference(P<0.05);the incidence of local ADR in Mirabilite for external use was low. CONCLUSIONS:Mirabilite combined with intraperitoneal has better efficacy in the elderly colorectal malignant ascites and better QOL.关键词
芒硝外敷/腹腔灌注/老年/恶性腹水Key words
Mirabilite for external use/Intraperitoneal/Elderly/Malignant ascites分类
医药卫生引用本文复制引用
周元,蒋红钢,陆伯豪,陈治横..芒硝外敷联合顺铂腹腔灌注治疗老年结直肠癌恶性腹水的临床观察[J].中国药房,2015,(20):2840-2842,3.