中国医科大学学报Issue(5)：401-406,6.
对比经皮冠状动脉介入治疗和小切口直接冠状动脉旁路移植术治疗前降支基底部狭窄的临床疗效的荟萃分析
A Systemic Review and Meta-analysis of Clinical Efficacy between Minimally Invasive Direct Coronary Bypass Grafting and Percutaneous Coronary Intervention for Stenosis Treatment of the Proximal Left Anterior Descending Artery
摘要
Abstract
Objective Percutaneous intervention(PCI)and minimally invasive direct coronary bypass grafting(MIDCAB)are the two well ac-cepted treatments for stenosis of the proximal left anterior descending artery. In order to better evaluate the therapeutic efficacy between these two methods,we performed a systemic review and meta-analysis of these studies. Methods PubMed,EMBASE and Cochrane were searched,and relat-ed data were retrieved. Stata12.0 was used to perform the meta-analysis. Results Totally 7 studies and 928 patients were recruited in this study,in-cluding 489 in PCI group and 439 in MIDCAB group. The results of meta-analysis revealed that patients in PCI group had a higher rate of repeat re-vascularization[relative risk(RR)=3.75,95%CI:2.3-6.11,P<0.01].No significant difference was found in neither all-cause mortality[RR=0.86, 95%CI:0.56-1.32,P=0.483]nor main adverse cardiovascular and cerebrovascular events(MACCE)[RR=1.64,95%CI:0.57-4.71,P=0.355]. Conclusion The therapeutic efficacy of MIDCAB were partially better than that of PCI.关键词
前降支基底部狭窄/经皮冠状动脉介入治疗/小切口冠状动脉旁路移植术/疗效Key words
stenosis of the proximal left anterior descending artery/percutaneous intervention/minimally invasive direct coronary by-pass grafting/therapeutic effects分类
医药卫生引用本文复制引用
张继倬,公兵,杨秀滨..对比经皮冠状动脉介入治疗和小切口直接冠状动脉旁路移植术治疗前降支基底部狭窄的临床疗效的荟萃分析[J].中国医科大学学报,2014,(5):401-406,6.基金项目
国家自然科学基金 （）
