孟丽伟 1杨彩哲 2关小宏 2吴石白 2王璐宁 2王敏2
作者信息
- 1. 河北北方学院研究生部，河北 张家口 075000
- 2. 空军总医院内分泌科，北京 100142
- 折叠
摘要
Abstract
Objective To establish a diagnostic scoring system for coronary artery disease(CAD)in patients with diabetic foot(DF)and evaluate its application efficiency. Methods The clinical data of 445 DF inpatients were analyzed retrospectively in this case⁃control study. These patients were divided into the CAD group(n=372,DF with CAD)and the control group(n=73,DF without CAD)according to the presence or absence of CAD. Risk factors were screened from related clinical factors examined through multiple logistic regression analysis for CAD in patients with DF and were assigned according to odds ratio(OR)to establish the scoring system for diagnosis of CAD in patients with DF. Application efficiency of the di⁃agnostic scoring system was tested by calculating area under the receiver operating characteristic(ROC)curve. Results The multiple logistic re⁃gression analysis showed that risk factors for CAD in patients with DF were age,male sex,the duration of diabetes≥10 years,the ankle⁃brachial in⁃dex(ABI)≤0.9,body mass index(BMI)≥25 kg/m2 and chronic renal insufficiency. According to ORassigned age(<50 years=0,50⁃64 years=1,≥65 years=2),sex(female=0,male=2),the duration of diabetes(<10 years=0,≥10 years=3),ABI(>0.9=0,≤0.9=2),BMI(<25 kg/m2=0,≥25 kg/m2=3)and chronic renal insufficiency(absent=0,present=3)scores. Area under the ROC curve of the diagnostic score scheme was 0.758(0.682⁃0.835),the standard error was 0.039,and the point of the diagnosis of CAD was 7. Conclusion The scoring system established in the study is efficacious,simple and practical,which provides an important reference for CAD in patients with DF.关键词
糖尿病足/冠心病/诊断评分系统/受试者工作特征曲线Key words
diabetic foot/coronary artery disease/diagnostic scoring system/receiver operating characteristic curve分类
医药卫生
