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Hrs对结肠癌细胞凋亡及增殖作用的研究

孙建秀 李璇

中国医科大学学报Issue(7):585-587,3.
中国医科大学学报Issue(7):585-587,3.

Hrs对结肠癌细胞凋亡及增殖作用的研究

Effects of Hrs on Apoptosis and Cell Proliferation in Colon Cancer Cell Lines

孙建秀 1李璇1

作者信息

  • 1. 中国医科大学附属第一医院血管/甲状腺外科,沈阳 110001
  • 折叠

摘要

Abstract

Objective To study the effects of Hrs on apoptosis and cell proliferation in colon cancer cell lines HCT⁃116 and SW⁃480. Methods The expression of Hrs in HCT⁃116 and SW⁃480 was knocking down by shRNA. Cell apoptosis was detected by FACS and cell proliferation was de⁃termined by MTT,incucyte and soft agar. Results The apoptosis was significantly increased after Hrs knocking down in both HCT⁃116 and SW⁃480,and the cell proliferation was inhibited. Conclusion Hrs is involved in the apoptosis and proliferation of colon cancer cells.

关键词

Hrs/结肠癌/凋亡/增殖

Key words

Hrs/colon cancer cell/apoptosis/proliferation

分类

医药卫生

引用本文复制引用

孙建秀,李璇..Hrs对结肠癌细胞凋亡及增殖作用的研究[J].中国医科大学学报,2015,(7):585-587,3.

基金项目

国家自然科学基金 ()

中国医科大学学报

OA北大核心CSCDCSTPCD

0258-4646

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