中国药理学通报Issue(12):1635-1638,4.DOI:10.3969/j.issn.1001-1978.2014.12.003
促红细胞生成素抗抑郁作用研究进展
Current progress of erythropoietin in depression
摘要
Abstract
Erythropoietin (EPO),which is routinely used in clinic to treat anemia,has been implicated in a wide range of activities on diverse tissues.Recently,accumulating evidence shows that EPO has antidepressant-like effects and may be a po-tential drug candidate for treating mood symptoms and memory dysfunction in depression.This review summarizes the current progress on EPO’s antidepressant-like effects,and explores its potential mechanism and clinical application in the future,provi-ding a general view of the research and application status of EPO in depression.关键词
促红细胞生成素/抑郁症/神经再生/抗炎/抗凋亡/衍生物Key words
erythropoietin/depression/neuranagenesis/anti-inflammatory/anti-apoptosis/derivative分类
医药卫生引用本文复制引用
李君玲,李玉波,薛晓兴,阎晶璐,王伟明,赵慧辉,王伟..促红细胞生成素抗抑郁作用研究进展[J].中国药理学通报,2014,(12):1635-1638,4.基金项目
国家重点基础研究发展计划(973计划)资助项目 ()