中国药理学通报Issue(12):1639-1641,3.DOI:10.3969/j.issn.1001-1978.2014.12.004
Micro RNA-106b-25簇与肿瘤
Role of micro RNA-106b-25 in cancer
摘要
Abstract
Micro RNA (miRNA)were small RNAs encoded by the non-coding RNA genes,which functioned through degrada-tion of mRNA or inhibition of mRNA translation.The miRNA was involved in numerous biological processes,including cell proliferation,apoptosis,development and differentiation.And ectopic expression of miRNA could result in diseases,such as neoplastic hematologic disorder and solid tumor.miR-1 06b-25 cluster contained miR-1 06b,miR-93 and miR-25.These miR-NAs were correlated with the development of tumor.Therefore, we reviewed recent articles on the relationship of miR-1 06b-25 cluster with tumor.关键词
miRNA/106b-25簇/肿瘤/凋亡/增殖/细胞周期Key words
miRNA/1 06b-25 cluster/tumor/apoptosis/pro-liferation/cell cycle分类
医药卫生引用本文复制引用
董曦,孙桂波,邢小燕,孙晓波..Micro RNA-106b-25簇与肿瘤[J].中国药理学通报,2014,(12):1639-1641,3.基金项目
国家科技部“重大新药创制”科技重大专项资助项目(No 2012ZX09501001-004);国家自然科学基金资助项目 ()