摘要
Abstract
Objective To maintain the effect of gastroesophageal reflux disease treatment mode factor analysis. Methods In this group,156 cases were selected,with the improvement of quality of life and reflux symptoms are grouped,the observation group,continuous medication,medication to al eviate symptoms,but once the drugs are stopped,wil be back in 1 weeks. The control group that even after the withdrawal wil not affect patients with normal work and life,and can last more than 1 weeks. Results 92 cases (58.97%) with on-demand treatment,64 cases (41.03%) by continuous treatment. Compared with the control group,the observation group Demeester integral and the duration significantly higher,with significant difference,with statistical significance (P<0.05).The observation group underwent endoscopic examination revealed a grade II~III RE patients accounted for 52.5%,while the control group underwent endoscopic examination revealed a grade II~III RE patients accounted for 10.9%,with more obvious differences,with statistical significance (P<0.05).The clinical efficacy and DECA (lower esophageal sphincter relaxation),UESP(upper esophageal sphincter pressure(LESP),lower esophageal sphincter pressure),percentage of inflammation,esophageal Demeester integral,course of disease,supine pH<4 there is a close connection. Conclusion For with abnormal anatomy,older age,severe nocturnal acid reflux,esophageal motility function,reflux symptoms in patients with severe can to maintenance therapy with continuous medication,worthy of further discussion.关键词
胃食管反流病/维持治疗/影响因素Key words
Gastroesophageal reflux disease/Maintenance treatment/Influencing factors分类
医药卫生
