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血必净注射液治疗重症急性胰腺炎的Meta分析

任杰 李倩 刘国恩

中国药物经济学Issue(9):9-13,5.
中国药物经济学Issue(9):9-13,5.

血必净注射液治疗重症急性胰腺炎的Meta分析

Meta-Analysis of Xuebijing Treating Severe Acute Pancreatitis

任杰 1李倩 1刘国恩1

作者信息

  • 1. 中国卫生经济研究中心,北京 100871
  • 折叠

摘要

Abstract

Objective To evaluate the efficacy of Xuebijing injection for the treatment of severe acute pancreatitis. Methods Literatures of RCT(randomized control ed trial)or CCT(clinical control ed trial)were selected to Meta-analysis. Results Five randomized clinical trials with 421 patients were included.Meta-analysis showed that the abdominal pain time(WMD=-1.86,95%CI:-2.27~-1.45,P=0.00001)、restoration time of blood and urine amylase (WMD=-1.80,95% CI:-2.68~-0.93,P<0.0001)、(WMD=-1.96,95% CI:-2.42~-1.50,P<0.00001)、restoration time of white blood cell(WMD=-2.49,95% CI:-3.56~-1.41,P<0.00001)and total efficiency(RR=1.16,95% CI:1.07~1.25,P=0.0002)of treatment group(Xuebijing+Ulinastatin+ based treatment)and the control group(Ulinastatin+based treatment) the difference were statistical y significant.Conclusion Current results indicated that the application of Xuebijing injection for the treatment of severe acute pancreatitis provided a shorter length of abdominal pain time、restoration time of blood(urine)amylase and white blood cell, and a higher total efficiency.

关键词

血必净/乌司他丁/重症急性胰腺炎/Meta分析

Key words

Xuebijing/Ulinastatin/Severe acute pancreatitis/Meta Analysis

分类

医药卫生

引用本文复制引用

任杰,李倩,刘国恩..血必净注射液治疗重症急性胰腺炎的Meta分析[J].中国药物经济学,2014,(9):9-13,5.

中国药物经济学

1673-5846

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