摘要
Abstract
Objective To know the efficacy of Xuebijing injection for the treatment of sepsis.Methods Literatures of RCT(randomized control ed trial) or CCT (clinical control ed trial) were selected to Meta-analysis.Results Four RCTs were included,with 181 patients in the treatment group were given Xuebijing+Ulinastatin+based treatment,181 patients in the control group were given Ulinastatin+basic treatment.Meta-analysis showed that the tumor necrosis factor(TNF-a)levels (WMD = -5.16,95% CI:-11.07~0.76)of experimental group and the control group were not statistical y different,but the interleukin(IL-6) levels(WMD=-57.82,95% CI:-112.12~-3.52),the procalcitonin(PCT) (WMD=-0.53,95% CI:-0.88~-0.19)levels,the average length of stay(WMD=-3.63,95% CI:-4.68~-2.58)and the average duration of mechanical ventilation[WMD=-3.77,95% CI (-4.70,-2.83)]of the treatment group and the control group were statistical y different.Conclusion Current results indicated that the application of Xuebijing injection for the treatment of sepsis provided a lower level of IL-6 and PCT,a shorter length of stay and duration of mechanical ventilation.关键词
血必净/乌司他丁/脓毒症/Meta分析Key words
Xuebijing/Ulinastatin/Sepsis/Meta Analysis分类
医药卫生
