摘要
Abstract
Objective To explore the clinical efficacy of antiviral therapy in hepatitis cirrhosis decompensation period patients.Methods Patients were colected in our hospital from 2012 June to 2014 data in June,hepatitis C cirrhosis 146 cases,according to the random number table method into two groups,each 73 cases,group A1 treated with pegylated interferon and ribavirin in the treatment of a-2a+,A2 group was treated with routine treatment. Comparison of two groups of treatment of liver function index 12,24 weeks after.Results The patients in the two groups after 12 weeks treatment,the comparison of TBIL,ALT,AST and HCV-RNA levels and before treatment,no significant difference(P>0.05);after 24 weeks of treatment,patients in group A1 TBIL,ALT,AST and HCV-RNA levels were significantly better than those in A2 group,the difference was statisticaly significant(P<0.05).Conclusion Pegylated interferon a-2a+ and ribavirin in the treatment of patients with hepatitis C cirrhosis,according to viral replication can be showed an obvious inhibition of liver function of patients can be improved evidently,the effect is obvious.关键词
丙型肝炎/肝硬化/代偿期/抗病毒治疗Key words
Hepatitis c/Cirrhosis/Compensatory period/Antiviral treatment分类
医药卫生
