中国药物经济学2015,Vol.10Issue(5):77-78,2.
两种剂量美托洛尔治疗老年不稳定型心绞痛药物不良反应对比分析
Clinical Comparative Analysis of Drug Adverse Reaction Incurred from two doses of Metoprolol in the Treatment of Elderly Patients with Unstable Angina
帕依扎·哈继木汗1
作者信息
- 1. 新疆布尔津县人民医院药剂科,新疆阿勒泰 836600
- 折叠
摘要
Abstract
Objective To investigate the difference of drug adverse reaction incurred from two doses of metoprolol in the treatment of elderly patients with unstable angina.Methods 160 elderly patients with unstable angina were chosen and divided into 2 groups including control group(80 patients)with metoprolol for (123 mg/d)and HR for 61 times/min and observation group(80 patients)with metoprolol for (171 mg/d)and HR for 50 times/min;and the clinical main event rate and adverse reactions occurrence with folowing up of both groups were compared.Results The clinical main event rate of observation group was significant better than control group(P<0.05).There was no significant difference in adverse reactions occurrence between 2 groups(P>0.05).Conclusion Larger doses of metoprolol in the treatment of elderly patients with unstable angina can efficiently improve the long-term prognosis and reduce the risk of adverse drug reaction.关键词
美托洛尔/不稳定型心绞痛/药物不良反应Key words
Metoprolol/Unstable angina/Drug adverse reaction分类
医药卫生引用本文复制引用
帕依扎·哈继木汗..两种剂量美托洛尔治疗老年不稳定型心绞痛药物不良反应对比分析[J].中国药物经济学,2015,10(5):77-78,2.