摘要
Abstract
Objective To evaluate the effect of acarbose in treatment of type 2 diabetes melitus(T2DM)economic benefit.Methods Colect the data of 88 cases of T2DM patients,the patients were randomly divided into two groups, 44 cases in each.A group of patients with acarbose in the treatment of patients in the B group,metformin treatment, compared two groups of patients with curative effect cost(C)/(E)ratio.Results The two groups after the treatment of FPG and 2 hPG were significantly lower than those before treatment(P<0.05),the two groups had no statisticaly significant differences in FPG level after treatment(P>0.05),but the 2 hPG A group was significantly lower than that in B group;FPG as indicators of efficacy,the difference between the two groups had no statistical signifi- cance(P>0.05); with 2 hPG as the standard of curative effect,the total effective rate of group A was significantly higher than that of B group(P<0.05);group A,2 FPG hPG C/E were 6.42,5.82,significantly higher than that of B group,3.25, 3.34(P<0.05); the adverse effects of the two groups compared, the difference was not statisticaly significance(P>0.05).Conclusion the therapeutic effect of acarbose and metformin control FPG quite, but the control effect of 2 hPG is better than that from the perspective of economics analysis of curative effect of metformin, acarbose and metformin, below the clinical medication,should be a reasonable choice according to the specific condition of patients.关键词
2型糖尿病/阿卡波糖/临床疗效/药物经济学Key words
Type 2 diabetes melitus/Acarbose/Clinical efficacy/Pharmacoeconomics分类
医药卫生