中国药物评价Issue(6)：345-349,355,6.
聚乙二醇干扰素治疗慢性丙型肝炎有效性的Meta分析
Meta-analysis of the Effectiveness on Peginterferon for Chronic Hepatitis C
陈平钰 1马爱霞1
作者信息
- 1. 中国药科大学国际医药商学院，江苏南京211198
- 折叠
摘要
Abstract
Objective:To systematically evaluate the clinical efficacy of peginterferon for Chinese chronic hepatitis C patients.Methods:The domestic chronic hepatitis C clinical trials adopting peginterferon published from 2004 to 2014 were retrieved,and SVR a-chieving rate was considered as clinical effective index to develop a Meta-analysis.Results:The SVR achieving rate between experimental group and control group was statistically different,among which the SVR achieving rate of the group adopting peginterferonα-2a was statis-tically different while the group adopting peginterferonα-2b was not.Conclusion:Peginterferon greatly improves the SVR achieving rate for Chinese chronic hepatitis C patients.Furthermore,peginterferonα-2a shows better clinical effect and peginterferon α-2b shows better safety.关键词
聚乙二醇干扰素/慢性丙型肝炎/Meta分析Key words
Peginterferon/Chronic hepatitis C/Meta-analysis分类
医药卫生引用本文复制引用
陈平钰,马爱霞..聚乙二醇干扰素治疗慢性丙型肝炎有效性的Meta分析[J].中国药物评价,2014,(6):345-349,355,6.
