兰索拉唑临床联合用药研究进展OA
Progress on Research of Lansoprazole Combined Drugs
目的:总结兰索拉唑( LPZ)联合药物治疗消化系统疾病以及与其他药物间相互作用的现状,为提高LPZ联合用药的安全性和有效性提供文献支撑。方法:对LPZ联合西药治疗消化系统疾病及其相互作用机制研究进行文献检索、分析与归纳。结果:LPZ主要通过抑酸作用治疗多种消化系统疾病,并可通过细胞色素P450、P-糖蛋白等多种机制影响联合用药药物的生物利用度。结论:今后需着重研究LPZ联合用药的作用机制、药效学评价和个体化用药差异,以确保联合用药的安全性和科学性。
Objective:Summary of lansoprazole combined with drugs in the treatment of digestive system diseases and drug interac-tions, and thinking on the related issues,in order to provide literature support for improving the safety and efficacy of lansoprazole com-bined drugs.Methods:This paper retrievalled,analysed and induced the studies of lansoprazole combined with western medicine in the treatment of digestive system diseases,and the interaction mechanism of lan…查看全部>>
王晓妍;孙蓉
山东中医药大学,山东济南250014山东省中医药研究院,山东济南250014
医药卫生
兰索拉唑联合用药药物相互作用
LansoprazoleDrug combinationDrug interaction
《中国药物评价》 2015 (1)
21-23,30,4
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