中国医学创新Issue(16)：4-6,3.DOI:10.3969/j.issn.1674-4985.2014.16.002
白三烯受体拮抗剂对吸烟哮喘患者病情控制的影响
Impact of Leukotriene Receptor Antagonist on the Disease Control of Smoking Asthmatic Patients
李剑 1赵晓宇 1吴泰华2
作者信息
- 1. 大连大学附属新华医院呼吸内科 辽宁 大连 116021
- 2. 大连医科大学附属第一医院呼吸内科
- 折叠
摘要
Abstract
Objective:To investigate the impact of leukotriene receptor antagonist on the disease control of smoking asthmatic patients.Method:110 smoking asthmatic patients in the outpatient clinic from March 2013 to December 2013 were selected.They were randomly divided into the control group for 54 cases and the treatment group for 56 cases according to the random number table method.The control group was treated with inhaled corticosteroid(budesonide), and inhaledβ2 agonist when necessary.The treatment group was treated with montelukast sodium for 4 weeks on the basis of the control group.Asthma Control Test(ACT)score,asthma-symptom score and morning and night PEF were compared between the two groups before and after treatment.Result:The ACT score,morning and night PEF%pred of the treatment group after treatment were significantly higher than before treatment and the control group,asthma-symptom score after treatment was significantly lower than before treatment and the control group,the differences were statistically significant (P<0.05).In the control group,the indicators before and after treatment comparison difference had no statistical significance(P>0.05).Conclusion:Leukotriene receptor antagonist can improve the control of disease,may be an effective drug in the treatment of smoking asthmatic patients.关键词
哮喘/吸烟/糖皮质激素/白三烯受体拮抗剂Key words
Asthma/Smoking/Corticosteroid/Leukotriene receptor antagonist引用本文复制引用
李剑,赵晓宇,吴泰华..白三烯受体拮抗剂对吸烟哮喘患者病情控制的影响[J].中国医学创新,2014,(16):4-6,3.
