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雄激素受体在雄性激素源性脱发患者的表达观察

梁皓 赵云杰 金磊 涂艳 陈波

中国医学创新Issue(18):60-62,3.
中国医学创新Issue(18):60-62,3.DOI:10.3969/j.issn.1674-4985.2014.18.020

雄激素受体在雄性激素源性脱发患者的表达观察

The Observation of Androgen Receptor Expression in Androgenetic Alopecia Patients

梁皓 1赵云杰 1金磊 1涂艳 1陈波1

作者信息

  • 1. 江西省九江市第一人民医院 江西 九江 332000
  • 折叠

摘要

Abstract

To investigate AR expression in the top of epidermis,hair follicle and sebaceous gland, sudoriferous gland.Method:The top and the occipital scalp of AGA patients(n=26)and the top scalp of non-alopecia people(n=10)as specimens were obtained,and AR expressions in the epidermis,hair follicle and sebaceous gland, sudoriferous gland were studied by immunohistochemistry method.Result:AR expressions of hair follicle,sebaceous gland,sudoriferous gland on the top of AGA patients were stronger than the occipital of AGA patients and the top of non-alopecia(P<0.05);AR expressions of hair follicle,sebaceous gland,sudoriferous gland in the occipital of AGA patients had no significant difference with the top of non-alopecia(P>0.05). All samples were negative for AR in epidermis. Conclusion:AR expressions on the top of hair follicle and sebaceous gland,sudoriferous gland in AGA patients may be one of the key factors leading to AGA.

关键词

雄性激素受体/雄性激素源性脱发

Key words

Androgen receptor/Androgenetic alopecia

引用本文复制引用

梁皓,赵云杰,金磊,涂艳,陈波..雄激素受体在雄性激素源性脱发患者的表达观察[J].中国医学创新,2014,(18):60-62,3.

基金项目

江西省卫生厅科技计划 ()

中国医学创新

1674-4985

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