摘要
Abstract
To investigate the efficacy of inhalation of budesonide and compound ipratropium bromide aerosol in treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Method:80 patients with AECOPD were randomly divided into the treatment group and the control group,40 cases in each group.The two groups were given basic treatment.The treatment group was given inhalation of budesonide and compound ipratropium bromide aerosol,and the control group was given salbutamol sulfate.The clinical curative effect,dyspnea score and changes of arterial blood gas indexes and lung function indexes before and after the treatment,the symptoms,signs of remission time and adverse reactions between the two groups were observed and compared.Result:After 10 days treatment,the total effective rate of the treatment group was 95.0%,it was significantly higher than 75.0%of the control group,and the improvements of dyspnea score,arterial blood gas indices such as PaO2 and PaCO2,lung function indices such as FEV1/FVC and PreFEV%of treatment group were significantly better than those of the control group,the index of the two groups after treatment were significantly better than before treatment,and the cough,shortness of breath, wheezing relief time,pulmonary symptoms disappear time in the treatment group were significantly shorter than the control group,the differences were statistically significant(P<0.05).Conclusion:The efficacy of inhalation of budesonide and compound ipratropium bromide aerosol in treatment of AECOPD is certain,and it is worthy of clinical application.关键词
布地奈德/复方异丙托溴铵/慢性阻塞性肺疾病/吸入Key words
Budesonide/Compound ipratropium bromide/Chronic obstructive pulmonary disease/Inhalation
