摘要
Abstract
To investigate the distribution and drug resistance of pathogenic bacteria in child patients with acute lower respiratory tract infection,to provide evidence for clinical anti infection treatment.Method:1622 sputum samples of child patients with acute lower respiratory tract infection from 2011 to 2013 were tested bacteria and drug sensitivity,the changes of pathogenic bacteria and drug resistance were analyzed statistically.Result:In 1622 specimens,659 strains pathogenic bacteria were isolated,the positive rate was 40.6%.420 strains were gram negative bacilli,accounted for 63.7%.203 strains were gram positive cocci,accounted for 30.8%.Klebsiella pneumoniae producing extended-spectrum β-lactamases were significant increasing trend.The top six pathogens were klebsiella pneumonia,escherichia coli,streptococcus pneumoniae,staphylococcus aureus,pseudomonas aeruginosa and bauman acinetobacter.The main antimicrobial susceptibility for staphylococcus aureus were vancomycin,rifampin, sulfonamides and amoxicillin/clavulanic,etc.The main antimicrobial susceptibility for streptococcus pneumoniae were vancomycin,gentamicin,chloramphenicol,ampicillin and cefazolin,etc.The main antimicrobial susceptibility for gram negative bacilli were meropenem,imipenem,the enzyme inhibitor drug,amikacin,ceftazidime and ampicillin,etc. Conclusion:Gram negative bacilli are the main pathogenic bacteria in child patients with acute lower respiratory tract infection.The main pathogens are multi drug resistance.Antimicrobial drugs should be used to standardize anti-infective therapy based on susceptibility results.Rational use of antimicrobial agents and reduce drug resistance.关键词
儿童/急性下呼吸道感染/病原菌/耐药性Key words
Children/Acute lower respiratory tract infection/Pathogenic bacteria/Drug resistance
