中国医学创新Issue(25)：123-124,2.DOI:10.3969/j.issn.1674-4985.2014.25.042
HBV-M与定量PCR法检测HBV-DNA相关性探析
The Correlative Analysis between HBV-M and HBV-DNA Detected by Quantitative Fluorescence PCR in Hepatitis B Patients
刘青鹤1
作者信息
- 1. 江西省广丰县人民医院 江西 广丰 334600
- 折叠
摘要
Abstract
Objective:To discuss the correlation between hepatitis B virus DNA and HBV-M.Method: Five hundred and forty-nine hepatitis B patients were selected in our hospital. Patients’ serum samples were collected, its HBV-DNA and HBV-M were detected by using quantitative PCR and enzyme-linked immunosorbent assay. The correlative between HBV-M and HBV-DNA was analyzed.Result: In HBsAg (+) + HBeAg (+) + HBcAb (+) mode, the positive rate of HBV-DNA was 97.9%. In HBsAg (+) + HBeAg (+) mode, the positive rate of HBV-DNA was 100%. The positive rates were not seen significant difference between the two modes, but they were significantly higher than the other modes(P<0.05).Conclusion: There are some correlations between serological markers of hepatitis B virus and HBV-DNA. HBV-M and HBV-DNA testing are circumstantial evidence and direct evidence of hepatitis B infection, while these two indicators of patient clinical diagnostic testing for hepatitis B, the condition determination, infectious assessment are of great significance.关键词
HBV-M/HBV-DNA/荧光定量PCR技术/相关性Key words
HBV-M/HBV-DNA/Fluorescence PCR/Correlative analysis引用本文复制引用
刘青鹤..HBV-M与定量PCR法检测HBV-DNA相关性探析[J].中国医学创新,2014,(25):123-124,2.
