中国医学创新Issue(26)：34-36,3.DOI:10.3969/j.issn.1674-4985.2014.26.013
贝那普利联合氨氯地平治疗高血压心力衰竭的疗效观察
Clinical Observation of Benazepril Combined with Amlodipine in Treatment of Hypertensive Heart Failure
许家本 1苏文源 1张宝红1
作者信息
- 1. 河南省洛阳市第九人民医院 河南 洛阳 471000
- 折叠
摘要
Abstract
Objective:To evaluate the effect of benazepril combined with amlodipine in treatment of hypertensive heart failure.Method:68 patients with hypertensive heart failure out patient wards in our hospital from January 2011 to August 2012 were selected,they were divided into the control group and the observation group according to the random number table method,34 cases in each group.The observation group was given amlodipine(5 mg/d)combined with benazepril(10 mg/d),the control group was only given benazepril(10 mg/d).12 weeks for a course of treatment.The antihypertensive effect and left ventricular diastolic function changes before and after treatment of the two groups were observed and compared.Result:The HR,SBP and DBP of the two groups after treatment were significantly lower than those of control group,the differences were statistically significant(P<0.05).But there was no statistically significant difference between two groups(P>0.05).The LVEDD reduction rate,LVESD reduction rate and LVEF improvement rate of observation group were significantly higher than those of control group,the differences were statistically significant (P<0.05).Conclusion:Benazepril combined with amlodipine treatment can significantly improve left ventricular function in hypertensive patients with heart failure,can reduce hypertension in patients with heart,brain,kidney,vascular complications,improve the quality of life of patients,curative effect is exact,high titer,is an ideal antihypertensive drugs.关键词
心力衰竭/高血压/贝那普利/氨氯地平Key words
Heart failure/Hypertension/Benazepril/Amlodipine引用本文复制引用
许家本,苏文源,张宝红..贝那普利联合氨氯地平治疗高血压心力衰竭的疗效观察[J].中国医学创新,2014,(26):34-36,3.
