摘要
Abstract
Objective:To analyze the clinical value of plasma homocysteine(Hcy)levels in patients with essential hypertension in predicting the occurrence of coronary heart disease(CHD). Method:Based on the results of coronary angiography,123 patients were divided into pure hypertension group(group A,n=64)and essential hypertension combined with CHD group(group B,n=59),the plasma homocysteine,blood fat,super sensitive c-reactive protein were analyzed. The logistic regression model was used to determine the risk factors for occurrence of CHD .Result:The lelve of Hcy,hs-CRP,HDL-C in group B were significant difference compared with those in group A(P=0.000),Logistic regression analysis results showed that the serum homocysteine was risk factor for the development of the occurrence of coronary heart disease[OR=1.116,95%CI(1.060,1.176),P=0.000].Conclusion:Hyperhomocysteinaemia has the prognostic value for the occurrence of CHD in patients with essential hypertension.关键词
原发性高血压/冠心病/同型半胱氨酸/超敏C反应蛋白Key words
Primary Hypertension/Coronary heart disease/Homocysteine/Super sensitive CRP
