中国医学创新Issue(27)：4-5,6,3.DOI:10.3969/j.issn.1674-4985.2014.27.002
婴幼儿毛细支气管炎患者血清IL-13、IL-8、TNF-α、TIgE水平的临床研究
Clinical Study of Serum IL-13,IL-8,TNF-α,TIgE Level in Children with Bronchiolitis
摘要
Abstract
Objective:To study the clinical significance on serum level of interleukin 13(IL-13),interleukin 8(IL-8),tumor necrosis factor(TNF-α),TIgE in infants with bronchiolitis. Method:36 cases of infantile with bronchiolitis(20 cases of the mild group and 16 cases of the severe group),and 30 cases of ordinary pneumonia,with 30 healthy infants were checked for the IL-13,IL-8,TNF-αand TIgE level with ELISA method.Result:The IL-13,IL-8, TNF-αlevel in the two groups of children with bronchiolitis and ordinary pneumonia were significantly higher than that in the normal control group(P<0.05);the IL-13,IL-8,TNF-α,TIgE level in the bronchiolitis group were higher than the ordinary pneumonia group(P<0.05);the level of TNF-αof the bronchiolitis severe group was higher than that in the mild group(P<0.05). Conclusion:IL-13,IL-8,TNF-αlevels play an important role in the process of bronchiolitis, and TNF-αlevel has association with the course and conditions of the disease;the serum level of TIgE is higher in the bronchiolitis infants than that of other control group.关键词
毛细支气管炎/婴幼儿/IL-13/IL-8/TNF-α/TIgEKey words
Bronchiolitis/Infants/IL-13/IL-8/TNF-α/TigE引用本文复制引用
王峻,李峰,王丽..婴幼儿毛细支气管炎患者血清IL-13、IL-8、TNF-α、TIgE水平的临床研究[J].中国医学创新,2014,(27):4-5,6,3.基金项目
山东省医药卫生科技攻关计划 （）
