中国医学创新Issue(28)：7-9,10,4.DOI:10.3969/j.issn.1674-4985.2014.28.003
术前血小板与淋巴细胞比值对结直肠癌预后的影响
The Effect of Platelet and Lymphocyte Ratio on the Prognosis of Colorectal Cancer
李小兵 1熊勇 1邹瑜斌 1徐满珍1
作者信息
- 1. 江西省新余市人民医院 江西 新余 338000
- 折叠
摘要
Abstract
Objective:To discuss the preoperative platelet/lymphocyte ratio(PLR)impact on the prognosis of patients with colorectal cancer.Method:150 patients with colorectal cancer from June 2007 to June 2012 in our hospital were selected as research objects.According to the results of routine blood tests before surgery ,calculating PLR.According to whether PLR<250,patients were divided into high-value group(PLR ≥ 250)for 22 cases and low-value group (PLR<250)for 122 cases.The clinical general information,five-year survival rate in different TNM stages and different degrees of differentiation of two groups were observed and compared.The effect of PLR on the prognosis of patients with colorectal cancer were investigated.Result:The proportion of colon cancer in high-value group was 67.86%(19/28),it was significantly higher than 45.90%(56/122)in low-value group,the proportion of undergoing laparoscopic surgery in high-value group was 14.29%(4/28),it was significantly lower than 40.16%(49/122)in low-value group,five-year survival rate of low-value group was 77.05%(94/122),it was significantly than 50.00%(14/28)of high-value group, The five-year survival rate of advanced cancer( Ⅲ, Ⅳstage)and differentiation of patients(patients with poor and mucinous)in high-value group were 28.57%(4/14)and 40.00%(4/10),they were significantly lower than 62.90%(39/62) and 75.00%(27/36)in low-value group,the differences were statistically significant(P<0.05).Conclusion:Five-year survival rate of high PLR value colorectal cancer patients is significantly lower than low PLR value patients.PLR is an important index to judge the prognosis of colorectal cancer patients,it is worth in clinical application..关键词
结直肠癌/血小板/淋巴细胞/5年存活率Key words
Colorectal cancer/Platelets/Lymphocytes/Five-year survival rate引用本文复制引用
李小兵,熊勇,邹瑜斌,徐满珍..术前血小板与淋巴细胞比值对结直肠癌预后的影响[J].中国医学创新,2014,(28):7-9,10,4.
