摘要
Abstract
Objective:To observe and analyze the clinical effect of tanshinone Ⅱ A sulfoacid sodium injection in treatment of cerebral infraction.Method:62 patients with cerebral infraction treated in our hospital from January 2011 to January 2014 were selected and divided into the research group and the control group according to completely randomized method 1:1,31 cases in each group.The control group was treated with routine Western Medicine, the research group was treated with tanshinone Ⅱ A sulfoacid sodium injection on the basis of control group,the neurological function and improvement of viability,free radical and hemarheology indicators change of the two groups were observed and compared.Result:Compared with before treatment,the SOD activity of two groups after treatment were significantly higher,MDA and LPO levels were significantly decreased(P<0.05).The SOD activity of research group after treatment was(5.96±0.13)U/mL,it was significantly higher than(4.85±0.11)U/mL of control group, the MDA level was(8.36±0.93)mol/mL and LPO level was(10.57±2.16)mol/mL,they were significantly lower than(10.54±0.52)mol/mL and(13.25±2.61)mol/mL control group,the differences were statistically significant (P<0.05).When the patients were treated for 2 weeks and 4 weeks,NIHSS and NDS score of two groups reduced,and ADL and BI score increased,and the differences between two groups were evident,which had statistical significance (P<0.05).The whole blood relative viscosity,plasma specific viscosity and aggregation index of red cells after treatment of the research group were significantly lower than those of before treatment and control group,the differences were statistically significant(P<0.05).Conclusion:Tanshinone Ⅱ A sulfoacid sodium injection in treatment of cerebral infraction has evident clinical effect,which is worthy of clinical promotion and application.关键词
丹参酮ⅡA璜酸钠/脑梗死/神经功能缺损程度/临床效果Key words
Tanshinone ⅡA sulfoacid sodium injection/Cerebral infraction/Neurological impairment degree/Clinical effect
