中国医学创新Issue(30)：110-111,112,3.DOI:10.3969/j.issn.1674-4985.2014.30.037
肥胖儿童血清25羟维生素D及胰岛素抵抗研究
Research of Serum 25-(OH)D Concentration and Insulin Resistance in Obese Children
摘要
Abstract
Objective:To investigate the relationship between childhood obesity and serum 25-(OH)D concentration and insulin resistance.Method:60 obese children aged 7 to 14 and 60 cases of normal weight children were selected. A fasting blood test was taken on serum 25-(OH)D concentrations,blood glucose and insulin. HOMA-IR was used to assess the level of insulin resistance. Tthe difference of serum 25-(OH)D concentration and insulin resistance was compared in the two groups.Result:The serum 25-(OH)D concentration of obese children was lower than that of normal children(P<0.01). HOMA-IR of obese children was higher than that of normal children. The difference was statistically significant(P<0.01). 25-(OH)D was negatively correlated with HOMA-IR(r=0.596,P<0.01). Conclusion:The serum 25-(OH)D concentration of obese children is lower than that of normal children. The level of insulin resistance of obese children is higher than that of normal weight children. Monitoring serum 25-(OH)D concentration in obese children and supply them with vitamin D is conductive to the improvement of insulin resistance and weight reduction.关键词
肥胖/儿童/25羟维生素D/胰岛素抵抗Key words
Obesity/Child/25-(OH)D/Insulin resistance引用本文复制引用
吴凡,徐定波,万方锐,胡新菊..肥胖儿童血清25羟维生素D及胰岛素抵抗研究[J].中国医学创新,2014,(30):110-111,112,3.基金项目
江西省卫生厅科技计划项目 （）
