中国医学创新Issue(31)：117-119,3.DOI:10.3969/j.issn.1674-4985.2014.31.040
盐酸羟考酮控释片联合加巴喷丁治疗癌性神经性疼痛疗效分析
Analysis on the Efficacy of Combined Therapy of Both Oxycodone Ketone Controlled Release Tablets and Gabapentin in the Treatment of Cancerous Neuropathic Pain
王娴 1熊盾 1杨波 1李海燕 1李秋宇1
作者信息
- 1. 云南省普洱市人民医院 云南 普洱 665000
- 折叠
摘要
Abstract
Objective:To observe the efficiency and side-effects of combined function of both oxycodone ketone controlled release tablets and gabapentin in the treatment of cancerous neuropathic pain. Method:Patients would be arranged in three groups:oxycodone ketone controlled release tablet monotherapy group(20 mg,Q12h,po). Combined therapy group(oxycodone ketone controlled release tablet:20 mg,Q12h,po;gabapentin:300 mg,Q12h,po). After 2 weeks treatment,the efficacy of both groups would be assessed. Result:The efficacy of monotherapy group was 70.83%(17/24)while that was 91.67%(22/24)in combined therapy group. There was significant difference in efficacy between the two groups(P<0.05). Side-effects as constipation,nausea and vomiting could be observed. Conclusion:Combined therapy of both oxycodone ketone controlled release tablets and gabapentin is significantly prior to monotherapy in the treatment of cancerous neuropathic pain. Combined therapy is feasible and can make the best of both medicine. It is worth further studying and widely clinical using.关键词
盐酸羟考酮控释片/加巴喷丁/癌痛/神经病理性疼痛/止痛Key words
Oxycodone ketone controlled release tablets/Gabapentin/Cancerous pain/Meuropathic pain/Pain relieving引用本文复制引用
王娴,熊盾,杨波,李海燕,李秋宇..盐酸羟考酮控释片联合加巴喷丁治疗癌性神经性疼痛疗效分析[J].中国医学创新,2014,(31):117-119,3.
