摘要
Abstract
Objective:To explore the clinical efficacy and impact on psychological scales of Butylphthalide in treatment of senile vascular dementia.Method:60 cases of vascular dementia patients were selected from our hospital during January 1,2012 and January1,2013,they were randomly divided into control group and experimental group,30 cases in each group.The control group patients were treated with traditional clinical treatment,and the experimental group patients were treated with Butylphthalide drug.The two groups’ treatment effect and the results of psychological scales were compared.Result:The experimental group’s treatment success rate was 86.67%and the control group’s treatment success rate was 50.00%,the experimental group was higher than control group,the difference was significantly(P<0.05);the experimental group’s complication rate was 6.67%,the control group’s complication rate was 20.00%,the experimental group was better than control group,the difference was significantly(P<0.05);the experimental group’s NMSE,ADL, CDR were(22.54±2.45)scores,(86.32±6.24)scores,(0.71±0.45)scores respectively,and the control group’s NMSE,ADL,CDR,were(15.45±3.23)scores,(46.12±7.34)scores,(1.68±0.52)scores respectively,the experimental group was better than control group,the difference was significantly(P<0.05).Conclusion:Butylphthalide used to treat enile vascular dementia patients has a good clinical efficacy,can significantly impact on the psychological scales,can improve the quality of life of patients,and has no significant adverse reactions,so it can be considered to promoted in clinical application.关键词
丁苯酞/老年血管性痴呆/临床疗效/精神心理量表Key words
Butylphthalide/Vascular dementia/Clinical efficacy/Psychological scales