中国医学创新Issue(36)：33-34,2.DOI:10.3969/j.issn.1674-4985.2014.36.012
大肠癌中STAT3、Twist的表达及与EMT关系的研究
Study on the Expression of STAT3, Twist in Colorectal Carcinoma and Its Relationship with EMT
摘要
Abstract
Objective:To investigate the expression of STAT3 in colorectal cancer, Twist and EMT (epithelial mesenchymal) relationship.Method:80 cases of adjacent tissues of colorectal cancer, cancer specimens were selected in our hospital, the expression of STAT3 and Twist and EMT related proteins were detected used immunohistochemical method.Result:Twist and STAT3 protein in colorectal cancer were significantly higher than the tissue adjacent to carcinoma (P<0.05). EMT in colorectal cancer were obviously lower than the tissue adjacent to carcinoma (P<0.05). The expression of STAT3 and Twist and EMT present positive correlation (P<0.05).Conclusion:SATA3 and Twist expression in colorectal cancer and no correlation between tumor biological characteristics, clinical detection of STAT3, Twist and EMT help predict tumor invasion and metastasis and prognosis.关键词
大肠癌/STAT3/Twist/EMTKey words
Colorectal cancer/STAT3/Twist/EMT引用本文复制引用
钟宝元..大肠癌中STAT3、Twist的表达及与EMT关系的研究[J].中国医学创新,2014,(36):33-34,2.基金项目
赣南医学院基础研究项目 （）
