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DPP-4抑制剂对糖尿病肾病的研究进展

韩海磊 柳洁

中国医学创新Issue(3):153-156,4.
中国医学创新Issue(3):153-156,4.DOI:10.3969/j.issn.1674-4985.2015.03.052

DPP-4抑制剂对糖尿病肾病的研究进展

The Research Progress of DPP-4 Inhibitors on Diabetic Nephropathy

韩海磊 1柳洁1

作者信息

  • 1. 山西医科大学第一临床医学院 山西 太原 030001
  • 折叠

摘要

Abstract

With the development of the occurrence of diabetes duration,all sorts of complications ensued,one of them is diabetic nephropathy.It is caused by the body state of sustained high blood sugar,while the DPP-4 inhibitors can reduce glucagon sample peptide-1(GLP-1) degradation,it can improve the body blood sugar state,in order to delay the progression of diabetic nephropathy.In addition,the DPP-4 in order to delay the progression of diabetic nephropathy. In addition,the DPP-4 can also affect other related to diabetic nephropathy of glp-1substrates,for example the BNP, activated protein C,the expression of HCY,et al,all have the protection of the kidney.The DPP-4 inhibitors on the protective effects of diabetic nephropathy,will provide a new direction in the treatment of diabetic nephropathy.

关键词

DPP-4抑制剂/糖尿病/糖尿病肾病

Key words

DPP-4 inhibitors/Diabetes/Diabetic nephropathy

引用本文复制引用

韩海磊,柳洁..DPP-4抑制剂对糖尿病肾病的研究进展[J].中国医学创新,2015,(3):153-156,4.

中国医学创新

1674-4985

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