中国医学创新Issue(5)：1-3,4,4.DOI:10.3969/j.issn.1674-4985.2015.05.001
血液灌流联合血液透析对尿毒症钙磷代谢及皮肤瘙痒的影响
Influence of Blood Perfusion Combined with Hemodialysis on Calcium and Phosphorus Metabolism and ;Skin Pruritus Symptoms of Patients with Uremia
冯敏坚 1刘新 1王文凤1
作者信息
- 1. 广东省中医院珠海医院 广东 珠海 519000
- 折叠
摘要
Abstract
Objective:To study influence of blood perfusion combined with hemodialysis on calcium and phosphorus metabolism and skin pruritus symptoms of patients with uremia. Method:42 uremia patients were selected as the research object.According to random number table method 42 patients were randomly divided into observation group and control group. Observation group:18 patients,treated with hemodialysis combing blood perfusion;Control group:24 cases,pure hemodialysis therapy. Calcium,phosphorus,skin pruritus conditions and quality of life of two groups before and after the treatment were compared. Result:4 weeks,8 weeks after treatment,serum calcium level of observation group was obviously improved than before the treatment(P<0.01),and the control group improved significantly during this period,and there were statistically significant difference(P<0.01);4 weeks,8 weeks after treatment,serum phosphorus levels of observation group was obviously improved before the treatment(P<0.01),and the control group improved significantly during this period,and there were significant difference(P<0.01). 4 weeks and 8 weeks after treatment skin pruritus in observation group were significantly better than before treatment,and also improved obviously than skin pruritus condition of patients in the control group at the same period,and there were statistically significant difference(P<0.001).The quality of life after treatment in observation group was obviously higher than that of control group,and the difference was statistically significant(P<0.001).Conclusion:Blood perfusion combined with hemodialysis can effectively correct uremia patients’ blood calcium and phosphorus metabolism disorder,and significantly reduce patients’ skin pruritus symptoms.关键词
尿毒症/血液灌流/血液透析/疗效Key words
5] Delporte C/Franck T/Noyon C/et al.Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS引用本文复制引用
冯敏坚,刘新,王文凤..血液灌流联合血液透析对尿毒症钙磷代谢及皮肤瘙痒的影响[J].中国医学创新,2015,(5):1-3,4,4.
