中国医学创新Issue(6):130-131,132,3.DOI:10.3969/j.issn.1674-4985.2015.06.043
氯氮平对男性精神分裂症患者骨密度的影响
Influence of Clozapine on Bone Mineral Density in Male Patients with Schizophrenia
杨宏亮 1王美娟 1张述杰 1赵路平 1李莉1
作者信息
- 1. 沈阳巿精神卫生中心 辽宁 沈阳 110168
- 折叠
摘要
Abstract
Objective: To investigate the effect of non-classical antipsychotic drugs on bone mineral density in male patients with schizophrenia.Method: The bone mineral density between the two groups were determinated with absorptiometry to learn bone mineral density. General situation was surveyed, combined with the general situation to analyze the related factors associated with bone density.Result: The normal BMD values in the case group and the control group was 30.00%, 81.25%, respectively, the osteoporosis in the case group and the control group was 52.50%, 6.25%, respectively. There were significant differences on BMD values between the two groups (P<0.05). There was no difference on age, body mass index between the two groups, there were differences in smoking, milk factors (P<0.05). Conclusion: Compared with the healthy population, the BMD on patients with the long-term use of antipsychotic drug significantly.关键词
非经典抗精神病药/氯氮平/精神分裂症/骨密度Key words
Non-classical antipsychotic drugs/Clozapine/Schizophrenia/Bone mineral density引用本文复制引用
杨宏亮,王美娟,张述杰,赵路平,李莉..氯氮平对男性精神分裂症患者骨密度的影响[J].中国医学创新,2015,(6):130-131,132,3.