中国医学创新Issue(7)：25-27,3.DOI:10.3969/j.issn.1674-4985.2015.07.008
硝酸镓对卵巢癌细胞蛋白表达的影响
Effects of Gallium Nitrate on Protein Expression of Ovarian Cancer Cells
杨红梅 1王学哲2
作者信息
- 1. 辽宁省锦州市太和区医院 辽宁 锦州 121001
- 2. 辽宁医学院附属第一医院
- 折叠
摘要
Abstract
Objective: To assess effect on ovarian adenocarcinoma cell HO-8910 by gallium nitrate, investigate the expression of Bcl-2, Bax and Caspase-3.Method: The human ovarian cancer cell line HO-8910 was cultured and treated with drugs, expression of Bcl-2, Bax and Caspase-3 was analyzed by Western blot.Result: The expression of Bcl-2 protein was down regulated in gallium nitrate group, cisplatin group and combination group compare with control. Bax and aspase-3 protein was activated in gallium nitrate group and combination group compare with control. Conclusion: Effects of gallium nitrate on human ovarian cancer cells, may be associating with the expression of Bcl-2 levels is decrease, Bax, Caspase are up regulation.关键词
硝酸镓/卵巢癌细胞/蛋白表达Key words
Gallium nitrate/Ovarian cancer cells/Expression of protein引用本文复制引用
杨红梅,王学哲..硝酸镓对卵巢癌细胞蛋白表达的影响[J].中国医学创新,2015,(7):25-27,3.
