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老年性痴呆患者脑功能和脑内神经递质变化的脑电超慢波涨落图分析

孙正海 赵玉环 王文林 董美宏 何东若 李平 韩云峰

中国医学创新Issue(10):62-64,3.
中国医学创新Issue(10):62-64,3.DOI:10.3969/j.issn.1674-4985.2015.10.021

老年性痴呆患者脑功能和脑内神经递质变化的脑电超慢波涨落图分析

The Analysis of the Encephal of Lutuograph Technology about the Brain Function and Brain Neurotransmitter Changes in Alzheimer’s Disease

孙正海 1赵玉环 1王文林 1董美宏 1何东若 1李平 1韩云峰1

作者信息

  • 1. 齐齐哈尔医学院精神卫生学院 黑龙江 齐齐哈尔 161006
  • 折叠

摘要

Abstract

Objective:To investigate the characteristic and significance of the brain function and the brain neurotransmitter changes in Alzheimer’s disease.Method:19 patients with clinically diagnosed AD were selected from the city proper of Qiqihar as the case group.According to the same community, sex, age (±3 years), and the educational level, 19 healthy elderly were selected as control group.To use the Encephal of lutuograph technology to test the brain function and the levels of their brain neurotransmitter, compare and analyze the brain function and the characteristic of the brain neurotransmitter changes in Alzheimer’s disease.Result:The anterior-posterior reversal rates of dominant power in encephal of lutuograph were higher in the case group than those of the control group (P<0.01).Compared with the control group, three neurotransmitters of the γ-GABA, Glu, and Ach in the case group were significantly lower (P<0.05).Comparison of three neurotransmitters of the 5-HT, NE, and the DA in the case group and the control group, the difference was not statistically significant.Conclusion:AD Brain power reversal rates are higher in Alzheimer’s disease than the case group.The brain neurotransmitter of γ-GABA, Glu, and Ach in Alzheimer’s disease changes lower.The Encephal of lutuograph technology can test the levels of brain neurotransmitter, provide reference for the diagnosis of Alzheimer’s disease.

关键词

老年性痴呆/脑功能/脑电超慢波涨落图技术/脑神经递质

Key words

Alzheimer’s disease/Brain function/Encephal of lutuograph technology/Brain neurotransmitter

引用本文复制引用

孙正海,赵玉环,王文林,董美宏,何东若,李平,韩云峰..老年性痴呆患者脑功能和脑内神经递质变化的脑电超慢波涨落图分析[J].中国医学创新,2015,(10):62-64,3.

基金项目

齐齐哈尔市科学技术局社会发展项目老年性痴呆患者脑神经递质变化及分布特点研究 ()

中国医学创新

1674-4985

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