中国医学创新Issue(18)：36-38,3.DOI:10.3969/j.issn.1674-4985.2015.18.013
P16、ER、CEA在宫颈腺癌和子宫内膜癌鉴别诊断中的临床意义
Analysis on Clinical Significance of P16,ER and CEA Joint Detection of the Cervical Adenocarcinoma and the Endometrial Carcinoma
摘要
Abstract
Objective:To observe and analysis the P16,ER and CEA protein expression in the cervical adenocarcinoma and endometrial adenocarcinoma and their clinical significance.Method:Immunohistoehemical method was used to detect P16,ER and CEA in paraffin-embedded tissues from 32 cases of endocervicaI adenocarcinomas and 32 cases of endometrial adenocarcinomas.The expression of P16,ER and CEA were retrospectively analyzed.Result:The positive rates of P16,ER, CEA in the cervical adenocarcinoma were 65.63%(21/32),28.13%(9/32),81.25%(26/32),respectively;those in endocervicaI adenocarcinoma were various 9.36%(3/32),75.00%(24/32),43.75%(14/32).P16 and CEA in the cervical adenocarcinoma positive expression rate were higher than those of endometrial adenocarcinoma(P<0.05).Endometrial adenocarcinoma in the positive rate of ER was obviously higher than that of the cervical adenocarcinoma(P<0.05). Conclusion:Joint detection expression of P16,ER and CEA protein has great clinical application value in the differential diagnosis of endocervical and endometrial adenocarcinomas.关键词
P16/ER/CEA/子宫颈腺癌/子宫内膜腺癌Key words
P16/ER/CEA/Cervical adenocarcinoma/Endometrial adenocarcinoma引用本文复制引用
杨伟洪,钟守军,段立峰,米贤军..P16、ER、CEA在宫颈腺癌和子宫内膜癌鉴别诊断中的临床意义[J].中国医学创新,2015,(18):36-38,3.基金项目
中山市卫生局立项课题 （）
