中国医学创新Issue(19)：1-5,6,6.DOI:10.3969/j.issn.1674-4985.2015.19.001
腹膜转运类型与腹膜炎、微炎症关系的研究
Observation on Relationship between Peritoneal Transport Type and Peritonitis,Microinflammatory
摘要
Abstract
Objective:To observe the microinflammatory,volume,nutritional indicators with different peritoneal transport type in CAPD patients before peritonitis occurs,and analyze the possible relationship between peritonitis, microinflammation and peritoneal transport type.Method:Patients proceeded the peritoneal equilibration test between first month and third month after accepting the peritoneal dialysis tube placement surgery.Group A (Non-fast transport) and group B (fast transport) were divided considered by the test result.The patients were detected lab indicators from the third peritoneal dialysis month,including hsCRP,IL-6,SBP,DBP,pro-BNP,PA,ALB,and then the same detection was conducted once every 2-4 months,which has been completed 4 times observe termination was event of peritonitis.Correlation analysis was done after the observation.Result:Group B showed a higher microinflammation,average blood pressure and pro-BNP level than group A, meanwhile the above indicators in patients with peritonitis were also higher than patients without peritonitis in peritoneal dialysis stage (P<0.05).The blood albumin,prealbumin both presented a lower level in group B than in group A,and in peritonitis patients than in non-peritonitis patients,with the time prolonged during the early dialysis stage,both in the observation group B presented descend trend significantly (P<0.05).IL-6 and hsCRP were correlated with PA and ALB negatively (P<0.05), and were correlated with pro-BNP as well as peritonitis positively in patients with fast peritoneal transport (P<0.05). Conclusion:The microinflammatory status is more serious in patients with peritoneal fast transport than those are not,which is correlated with volume overload and poor nutrition status,the three factors plays an important role in the development of the fast peritoneal transport patients with peritonitis by interact causally.关键词
腹膜炎/腹膜转运类型/微炎症Key words
Peritonitis/Peritoneal transport/Micrinflammation引用本文复制引用
林克宣,雷蕾,黄成文,郑庆发,白建祥,黄润浓,石咏军,刘冠贤..腹膜转运类型与腹膜炎、微炎症关系的研究[J].中国医学创新,2015,(19):1-5,6,6.基金项目
广东省医学科学技术研究基金 （）
