中国医学创新Issue(19):63-65,3.DOI:10.3969/j.issn.1674-4985.2015.19.021
急性颅脑损伤血清P-选择素监测的临床价值
The Clinical Value of Serum P-selectin in Monitor of Acute Brain Injury
彭昌海 1彭俊云 1叶建俊1
作者信息
- 1. 广东省高要市人民医院 广东 高要 526040
- 折叠
摘要
Abstract
Objective:To investigate the clinical value of serum P-selectin in monitor of patients with acute brain injury. Method:90 patients with acute brain injury were divided into light group (30 cases),medium group (30 cases) and severe group (30 cases) according to GCS scores.The expression levels of serum P-selectin and D-Dimer 1 d after onset in the three groups were detected.While 30 healthy outpatients were selected as control group,the expression levels of serum P-selectin and D-Dimer 1,3,and 7 d after onset in the control group and patients with acute brain injury were detected.Result:The expression levels of serum P-selectin and D-Dimer of patients with acute brain injury were significantly higher than that of the control group (P<0.05),and with the clinical classification gradually increased,the expression levels of serum P-selectin and D-Dimer significantly increased (P<0.05).The expression levels of serum P-selectin and D-Dimer in patients with acute brain injury 1,3 and 7 d after onset were significantly higher that of the control group (P<0.05),and with the gradual onset date prolonged,the expression levels of serum P-selectin and D-Dimer were significantly lower (P<0.05).The expression of serum P-selectin had a positively correlated with the expression of D-Dimer (P<0.05).Conclusion:Serum P-selectin has a high clinical value in assess of severity and outcome aspects of patients with acute brain injury.关键词
急性颅脑损伤/P-选择素/D-二聚体Key words
Acute brain injury/P-selectin/D-dimer引用本文复制引用
彭昌海,彭俊云,叶建俊..急性颅脑损伤血清P-选择素监测的临床价值[J].中国医学创新,2015,(19):63-65,3.