中国医学创新Issue(20)：1-5,5.DOI:10.3969/j.issn.1674-4985.2015.20.001
单中心腹膜透析相关性腹膜炎危险因素分析
Research on Risk Factors of Peritoneal Dialysis Related Peritonitis in a Single Center
摘要
Abstract
Objective:To analyze the clinical data of continuous ambulatory peritoneal dialysis patients confronted with peritonitis retrospectively and to discuss the risk factors in the occurrence and the prognosis of peritonitis.Method:The peritoneal dialysis patients who planted with peritoneal dialysis catheter and were long-term fixed in our follow-up in our hospital from January 2008 to December 2013 were retrospectively analyzed.(1)Patients were divided into two groups according to whether they had peritonitis or not,patients in group A had peritonitis and patients in group B were free of peritonitis.The clinical data of the time when they were placed tubes was compared and the related risk factors were analyzed.(2)On the basis of therapeutic effect,peritonitis patients were divided into group 1(symptoms recurrent or quit peritoneal dialysis) and group 2(healing by formal treatment),the two groups were also compared in the aspects of clinical characteristics and lab data. Result:(1)The educational status,levels of hemoglobin,albumin and serum potassium in group A were lower than those in group B,diastolic blood pressure was higher than the group B,the result was opposite when it came to the proportion of diabetes patients and fast peritoneal transport patients,the differences between the two groups were statistically significant(P<0.05 or P<0.01).Logistic regression analysis showed that diabetes as the basic diseases,hemoglobin≤80 g/L,albumin≤30 g/L and peritoneal rapid transport type were the risk factors for the occurrence of peritoneal dialysis related peritonitis.(2)Group 1 showed a higher average age,proportion of high sugar concentration solution employment≥2 bags/day,proportion of diabetes patients and proportion of patients with peritoneal rapid transport type but a lower albumin level than group 2,the differences were statistically significant(P<0.05 orP<0.01).Logistic regression suggested that albumin≤30 g/L,diabetes and the use of high sugar concentration solution≥2 bags/day were risk factors of poor prognosis.Conclusion:Patients with low educational status,low level of hemoglobin concentration,hypoalbuminemia,hypokalemia,diabetes and fast peritoneal transport have higher possibility to get peritonitis,hemoglobin≤80 g/L,albumin≤30 g/L,diabetes and peritoneal fast transport are the risk factors of peritonitis.Peritonitis patients with elderly age,a higher proportion of high sugar concentration solution employment,diabetes and rapid peritoneal fast transport should be alert to the occurrence of adverse outcome,meanwhile,albumin≤30 g/L, diabetes and the use of high sugar concentration solution are risk factors of poor prognosis.关键词
腹膜炎/腹膜快速转运/危险因素Key words
Peritonitis/Fast peritoneal transport/Risk factors引用本文复制引用
黄成文,雷蕾,林克宣,郑庆发,白建祥,姚嘉萍,石咏军,刘冠贤..单中心腹膜透析相关性腹膜炎危险因素分析[J].中国医学创新,2015,(20):1-5,5.基金项目
广东省医学科学技术研究基金 （）
