摘要
Abstract
ObjectiveTo study the relation of esophageal motility and acid relfux between gastroesophageal reflux disease (GERD) patients with and without esophageal injury.Methods75 cases of patients with gastroesophageal reflux from January 2012 to August 2013 were conducted esophageal-gastric-duodenal endoscopy examination and followed with high-resolution esophageal manometry, and detected the changes of esophageal pH postprandial,. The differences of esophageal motility and acid relfux time between esophageal injury group and without esophageal injury group were compared, and the changes of esophageal motility indexes between non acid relfux and acid relfux group were compared whether there is statistical signiifcance. ResultsThere was no significant difference in baseline value of lower esophageal sphincter pressure, remained lower esophageal sphincter pressure, speed of the esophageal peristalsis, the time of esophageal pH<4 and DeMeester score between groups with and without esophageal injury (allP>0.05), esophageal contraction amplitude of group with without esophageal injury was higher than that of esophageal injury group, which had signiifcant difference (P<0.05). There was no signiifcant difference in baseline value of ower esophageal sphincter pressure, remained LES pressure, speed of the esophageal peristalsis between acid relfux group and non acid relfux group (allP>0.05), the esophageal contraction amplitude of acid relfux group was lower than that of non acid relfux group, which had signiifcant difference (P<0.05). The difference was not statistically signiifcant.ConclusionsThere was no signiifcant correlation between the lower esophageal sphincter pressure and esophageal acid relfux with esophageal injury in GERD patients. But esophageal peristalie contraction may be associated with esophageal injury and acid relfux.关键词
胃食管反流病/食管损伤/食管动力/酸反流/相关性Key words
Gastroesophageal relfux/Esophageal injury/Esophageal motility/Acid relfux/Relativity
