摘要
Abstract
Objective To explore the clinical efifcacy on lamivudine treatment combination with reasonable nutrition plan for decompensated cirrhosis patients due to hepatitis B. Method 96 patients with decompensated cirrhosis in our hospital were included into this study. They were divided into the control group and the observation group. The observation group was treated with lamivudine and reasonable nutrition plan, the control group was treated with the comprehensive treatment. To sort and analyse the following variables:HBV-DNA level, ALT, ALB, TBIL and the rate of hepatocellular carcinoma, death rate at the 12, 24, 36 months. Result The liver function, serum virological indicators and after treatment were better than pre treatment in two group (P<0.05), the TBIL, ALT, Child-Pugh in control group was higher than that of observation group. The differences were signiifcant (P<0.05);the HBeAg and HBV-DNA negative in observation group was higher than that of control group. The differences were signiifcant (P<0.05);the rate of hepatocellular carcinoma, death rate at the 12, 24, 36 months in observation group was lower than that of control group. The differences were signiifcant (P<0.05). Conclusion Lamivudine treatment combination with reasonable nutrition plan for decompensated cirrhosis patients due to hepatitis B can effectively improve the clinical efifcacy and reduce the hepatocellular carcinoma and death rate.关键词
拉米夫定/失代偿期肝硬化/乙型肝炎Key words
Lamivudine/Decompensated cirrhosis/Hepatitis B
