中国医学前沿杂志（电子版）Issue(9)：45-48,4.
宫颈特殊染色法上皮组织特殊染色液在宫颈病变检查中的临床意义
Clinical signiifcance of FRD in epithelial tissue special staining solution in the examination of cervical lesions
摘要
Abstract
Objective To explore the use of cervical special staining of folate receptor mediated FRD clinical value of epithelial tissue special staining solution to inspect the cervical lesion, provide the method reference for the early detection of cervical lesions. Method From January 2014 to April 2014 jointed national hospital for a gynecological examination randomly 2000 cases of women screening, detection liquid based thin-layer cell line (TCT), human papilloma virus (HPV), FRD staining, theparts in pathology as the gold standard. Please check the histopathology as the gold standard, the diagnosis was the detection method of the evaluation standard. Result FRD detected 130 cases of patients with positive, positive rate was 6.5%;the sensitivity was 83.06%, speciifcity was 98.56%, the misdiagnosis rate was 16.94%, the misdiagnosis rate was 1.44%, Kappa=0.821, P=0.000. There were 125 cases of TCT positive patients, the positive rate was 6.255%;the sensitivity was 86.29%, speciifcity was 99.04%, the misdiagnosis rate was 13.71%, the misdiagnosis rate was 0.96%, Kappa=0.850, P=0.000. There were 120 cases of HPV positive patients, the positive rate was 6%;the sensitivity was 79.84%, speciifcity was 98.88%, the misdiagnosis rate was 20.16%, the misdiagnosis rate was 1.12%, Kappa = 0.806, P = 0.000. Three methods of inspection detection rate from high to low were FDR, TCT6, HPV, but the positive rate was not significantly difference (χ2 = 0.427, P = 0.808). Conclusion TCT > FRD > HPV consistency of three methods but the detection rate has no signiifcant difference, with the traditional TCT, HPV checks the same detection efifciency of the FRD detection method, but its characteristics with more convenient, fast, economy, worth as a rapid screening method for application.关键词
宫颈特殊染色法/上皮组织/宫颈癌病变Key words
FRD/Epithelial tissue/Cervical lesions引用本文复制引用
张朝红,黄玮,薛晓玲,王兰妮,孙晓丽..宫颈特殊染色法上皮组织特殊染色液在宫颈病变检查中的临床意义[J].中国医学前沿杂志（电子版）,2014,(9):45-48,4.基金项目
陕西省卫生厅科研基金 （）
