摘要
Abstract
Objective To investigate the clinical efifcacy of routine anti heart failure drug therapy combined with spironolactone perindopril in treatment of heart failure. Method 112 patients with heart failure in our hospital were selected. They were randomly divided into observation group and control group with 56 patients in each. Control group was given conventional treatment combined with perindopril, while observation group treated based on control group, then combined with spironolactone. The total efifciency and heart functional grade were compared between two groups. Result The total effective rate of observation group was 96.43%, while control group was 62.50%, which showed significant difference (P < 0.05), the number of cardiac functional grading forⅠ,Ⅱ,Ⅲ,Ⅳin observation group was 24, 17, 10, 5 cases, respectively;while in control group, they were 3, 14, 13, and 26 cases. The cardiac functional grading of observation group was better than control group, there was signiifcant difference (P < 0.05). Conclusion The conventional anti heart failure drug therapy combined with spironolactone perindopril for the treatment of heart failure, can improve the total efifciency and cardiac function in patients.关键词
心力衰竭/螺内酯/培哚普利/临床疗效Key words
Heart failure/Spironolactone/Perindopril/Clinical effect
