摘要
Abstract
ObjectiveInvestigate the clinical value of tiroifban combined with aspirin, clopidogrel and low molecular heparin for elderly patients with acute non ST segment elevation myocardial infarction (USTAMI). Method148 patients with USTAMI were randomly divided into observation group and control group, 74 cases in each group, observation group were given tiroifban combined with aspirin, clopidogrel and low molecular heparin treatment, control group were given aspirin, low molecular weight heparin. Compared myocardial infarction after 6 hours of creatine kinase isoenzyme (CK-MB), cardiac troponin (cTnI), CK-MB, cTnI peak time and 30 days left ventricular ejection fraction (LVEF) of two groups.ResultThe concentrations of LVEF, CK-MB and cTnI had no signiifcant difference between pre-treatment and after 30 days of treatmen (P>0.05). The concentrations of CK-MB and cTnI were signiifcant higher after 6 hours of treatment than pre-treatment, and the concentation of LVEF were signiifcantly improved after 30 days of treatment (P<0.05). And the rising rate of the concentration of CK-MB and cTnI were signiifcantly slower in observation group than that in control group (P<0.05), the increase of the concentration of LVEF was more obviously in observation group than that in control group (P<0.05), and the period to the peak concentration of CK-MB and cTnI were signiifcantly shorter than that in control group (P<0.05).ConclusionTiroifban combined with aspirin, low molecular heparin for elderly acute in patients with non ST segment elevation myocardial infarction is better than aspirin with Clopidogrel and low molecular heparin.关键词
替罗非班/阿司匹林/氯吡格雷/非ST段抬高型心肌梗死Key words
Tiroifban/Aspirin/Clopidogrel/Non ST segment elevation myocardial infarction