中国医学前沿杂志（电子版）Issue(10)：123-125,3.
戈舍瑞林联合阿那曲唑治疗绝经前高危乳腺癌的临床研究
Clinical study of goserelin combined with anastrozole for premenopausal highrisk breast cancer patients
江歌丽 1朱宁生 1周鑫 1何笑冬 1熊忠讯 1于峰 1曾晓华1
作者信息
- 1. 重庆市肿瘤医院 重庆市肿瘤研究所 乳腺中心，重庆 400030
- 折叠
摘要
Abstract
ObjectiveTo investigate the clinical effect of goserelin combined with endocrine therapy for premenopausal high-risk breast cancer patients.Method90 cases of patients with breast cancer were confirmed by pathology in our hospital from March 2010 to July 2012, which were treated by goserelin combined with anastrozole and observed the curative effects and side effects.ResultThe ORR was 17.8%, CB was 68.9%; the survival rate in visceral metastases patients was signiifcantly higher than patients with no visceral metastases; analyzed the factors related to the survival rate of the patients showed that the visceral metastasis was the independent prognostic factors for patients; the incidence of adverse reaction was 37.8%, the most common were hectic fever, nausea, the degree was all in patient tolerance range.ConclusionIt is safe and effective of goserelin combined with endocrine therapy for premenopausal high-risk breast cancer patients.关键词
乳腺癌/戈舍瑞林/阿那曲唑/临床疗效/不良反应Key words
Breast cancer/Goserelin/Anastrozole/Clinical effect/Adverse reaction引用本文复制引用
江歌丽,朱宁生,周鑫,何笑冬,熊忠讯,于峰,曾晓华..戈舍瑞林联合阿那曲唑治疗绝经前高危乳腺癌的临床研究[J].中国医学前沿杂志（电子版）,2014,(10):123-125,3.
