摘要
Abstract
Objective To discuss the clinical effects and safety of lfurbiprofen preemptive analgesia to prevent general anesthesia emergence agitation of lobectomy. Method 60 cases of patients underwent lobectomy were randomly divided into observation group and control group, 30 cases in each group, all underwent conventional induction anesthesia, surgery patients were given remifentanil, propofol, vecuronium infusion to maintain anesthesia, observation group patients before 30 minutes disposable intravenous injection of lfurbiprofen 1 mg/kg, patients in control group intravenous injection of 5 ml of physiological saline. Two groups of patients were observed with restless score, bleeding time, extubation time, the time of anesthesia and the incidence of adverse reactions. Result Observation group patients restlessness score was (0.88±0.34) points, signiifcantly lower than that of control group [(1.89±0.53) points], the difference was signiifcant (P<0.05);two groups of patients anesthesia time, bleeding time, extubation time there was no significant difference (P>0.05). Observation group after operation dizziness headache was 3 cases (10%), nausea and vomiting was 9 cases (30.00%), chills and fever was 1 case (3.33%), heart palpitations was 3 cases (10%), somnolence was 2 cases (6.67%), control group of patients with dizziness headache was 5 cases (16.67%), nausea and vomiting was 11 cases (36.67%), chills and fever was 2 cases (6.67%), heart palpitations was 1 case (3.33%), somnolence was 4 cases (13.33%), the incidence of adverse reactions in two groups were not signiifcant (P > 0.05). Conclusion Flurbiprofen injection for prevention of general anesthesia emergence agitation of lobectomy is effective, and does not increase the adverse reaction of patients, worthy of clinical application.关键词
氟比洛芬酯/超前镇痛/肺叶切除术/全身麻醉/苏醒期躁动Key words
Flurbiprofen/Preemptive analgesia/Lobectomy/General anesthesia/Emergence agitation
